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| Product Name | LDLRAP1, 1-308aa, Human, His tag, E Coli |
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| Description | MW: 36.1kDa (328aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. LDLRAP1 (Low density lipoprotein receptor adapter protein 1) is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. LDLRAP1 is a cytosolic adaptor that couples LDLR to endocytic machinery. Defects in LDLRAP1 are the cause of autosomal recessive hypercholesterolemia (ARH). ARH is a disorder caused by defective internalization of LDL receptors (LDLR) in the liver. Recombinant human LDLRAP1 protein, fused t |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Low density lipoprotein receptor adaptor protein 1; ARH; ARH1; ARH2; FHCB1; FHCB2] |
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| Gene, Accession, CAS # | LDLRAP1, Gene ID: 26119, Accession: AAH29770 |
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| Catalog # | MBS204342 |
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| Order / More Info | LDLRAP1, 1-308aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Garcia C.K., et al. (2001) Science 292:1394-1398; Mishra S.K., et al. (2005) J. Biol. Chem. 280:19270-19280 |
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