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| Product Name | LDLR chaperone MESD, 30-224aa, Mouse, His tag, E Coli |
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| Description | MW: 24.4kDa (218aa). Purity >90% by SDS-PAGE. MESDC2 also known as LDLR chaperone MESD. This protein is specialized chaperone for low-density lipoprotein receptor-related protein 5 and LRP6. MESDC2 binds to mature LRP6 on the cell surface and blocks the binding of Wnt antagonist Dickkopf-1 to LRP6. Furthermore, MESDC2 plays an essential role in NMJ formation by promoting Lrp4 maturation. Recombinant mouse MESDC2, fused to His-tag at N-terminus was expressed in E Coli and purified by using conven |
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| Size | 0.02 mg, 0.1 mg |
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| Concentration | 1mg/ml (determined by Absorbance at 280nm) |
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| Applications | SDS-PAGE |
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| Other Names | [2210015O11Rik; AW537813; mesd; mKIAA0081; msd] |
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| Gene, Accession, CAS # | LDLR, Gene ID: 67943, Accession: NP_075892 |
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| Catalog # | MBS206270 |
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| Order / More Info | LDLR chaperone MESD, 30-224aa, Mouse, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Lu W., et al. (2010) Biochemistry. 49 (22): 4635-43.; Hoshi T., et al. (2013) FEBS Lett. 587 (23): 3749-54. |
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