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| Product Name | SYK, Recombinant, Human, GST-Tag (Spleen Tyrosine Kinase, p72Syk, Tyrosine Protein Kinase SYK) |
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| Description | Purified (~70-90%). SYK is a non-receptor protein tyrosine kinase that is widely expressed in hematopoietic cells. It is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. In B cells, SYK plays a crucial role in intracellular signal transduction induced by oxidative stress as well as antigen receptor engagement. SYK has been shown to act as a potential tumor suppressor in breast cancer. Absence of SYK protein in primary breast tumors is correlated with poor outcomes. SYK deficient cells have increased motility that is restored to normalcy by replacement with wild-type SYK. Source: Recombinant protein corresponding to human SYK, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~100kD Specific Activity: 92nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_003177, SwissProt: P43405 |
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| Catalog # | 500474 |
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| Order / More Info | SYK, Recombinant, Human, GST-Tag (Spleen Tyrosine Kinase, p72Syk, Tyrosine Protein Kinase SYK) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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