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| Product Name | OxiSelect Comet Assay Kit (3-Well Slides) |
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| Description | OxiSelect Comet Assay is a single cell gel electrophoresis assay (SCGE) for simple evaluation of cellular DNA damage. First, individual cells are mixed with molten agarose before application to the OxiSelect Comet Slide. These embedded cells are then treated with a lysis buffer and alkaline solution, which relaxes and denatures the DNA. Finally, the samples are electrophoresed in a horizontal chamber to separate intact DNA from damaged fragments. Following electrophoresis, the samples are dried, |
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| Size | 75 assays, 375 assays, |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS168415 |
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| Order / More Info | OxiSelect Comet Assay Kit (3-Well Slides) from MYBIOSOURCE INC. |
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| Product Specific References | 1. Ostling, O., and Johanson, K. J. (1984). Biochem. Biophys. Res. Commun. 123, 291-298.2. Singh, N. P., McCoy, M. T., Tice, R. R., and Schneider, E. L. (1988). Exp. Cell. Res. 175, 184-191.3. Olive, P. L., Banath, J. P., and Durand, R. E. (1990). Radiat. Res. 122, 86-94.4. De Boeck, M., Touil, N., De Visscher, G., Vande, P. A., and Kirsch-Volders, M. (2000). Mutat. Res. 469, 181-1971. Wang, L. et al. (2014). Osmotic Stress-induced Phosphorylation of H2AX by Polo-like Kinase 3 Affects Cell Cycle Progression in Human Corneal Epithelial Cells. J Biol Chem. 289:29827-29835.2. Savage, K.I. et al. (2014). BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability. Cancer Res. 74:2773-2784.3. Robin, T.P. et al. (2012). EWS/FLI1 Regulates EYA3 in Ewing Sarcoma via Modulation of miRNA-708, Resulting in Increased Cell Survival and Chemoresistance. Mol. Cancer Res. 10:1098-1108.4. Choi, S.K. et al. (2012).Poly(ADP-Ribose) Polymerase 1 Inhibition Improves Coronary Arteriole Function in Type 2 Diabetes Mellitus. Hypertension. 59:1060-1068. |
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