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| Product Name | OxiSelect DNA Double-Strand Break (DSB) Staining Kit |
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| Description | Background: DNA double-strand breaks (DSBs) are probably the most dangerous of the many different types of DNA damage that occur within the cell. DSBs are generated by exogenous agents such as ionizing radiation (IR) or by endogenously generated reactive oxygen species and occur as intermediates during meiotic and V(D)J recombination. A very early step in the cellular response to DSBs is the phosphorylation of a histone H2A variant, H2AX, at the sites of DNA damage. H2AX is rapidly phosph |
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| Size | 20 Assays, 100 Assays |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [OxiSelect DNA Double-Strand Break (DSB) Staining Kit] |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS168496 |
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| Order / More Info | OxiSelect DNA Double-Strand Break (DSB) Staining Kit from MYBIOSOURCE INC. |
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| Product Specific References | 1. Rogakou, E. P., Pilch, D. R., Orr, A. H., Ivanova, V. S., and Bonner, W. M. (1998) J. Biol. Chem. 273, 5858-5868. 2. Rogakou, E. P., Boon, C., Redon, C., and Bonner, W. M. (1999) J. Cell Biol. 146, 905-915. 3. Paull, T. T., Rogakou, E. P., Yamazaki, V., Kirchgessner, C. U., Gellert, M., and Bonner, W. M. (2000) Curr. Biol. 10, 886-895. 4. Chen, H. T., Bhandoola, A., Difilippantonio, M. J., Zhu, J., Brown, M. J., Tai, X., Rogakou, E. P., Brotz, T. M., Bonner, W. M., Ried, T., and Nussenzweig, |
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