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| Product Name | Myelin, Oligodendrocyte Glycoprotein, 44-54 (OMgp, MOG) |
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| Description | Purity ~90% as determined by RP-HPLC, MS. This 11mer peptide myelin oligodendrocyte glycoprotein ( pMOG) (44-54) represents the core binding epitope for MOG-specific CD8+ T cells. This is the minimal, functionally constant, length of the MOG (35-55) peptide that binds to CD8+ MOG-specific T cells and stimulates T cell proliferation in vitro. MOG peptide (35-55) is highly encephalitogenic and can induce strong T and B cell responses. A single injection of this peptide produces a relapsing- remitting neurologic disease with extensive plaque-like demyelination. Because of the clinical, histophathologic, and immunologic similarities with multiple sclerosis (MS), the MOG induced demyelinating encephalomyelitis may serve as a model for investigating MS. Amino Acid Composition: H-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-OH. Solubility: It is recommended to reconstitute the lyophilized MOG in sterile 18Mω-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueou |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | M9758-08E |
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| Order / More Info | Myelin, Oligodendrocyte Glycoprotein, 44-54 (OMgp, MOG) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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