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Product Name | RAB27A, aa1- 221, Recombinant, Human |
Description | Purity ~90% (SDS-PAGE). Ras-related protein Rab-27A, also known as RAB27A, belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Also, RAB27A regulates the cytotoxic granule exocytosis and affect T-lymphocyte and macrophage-activation. It is widely expressed with significant expression in pancreatic islets and pituitary tissue, and low expression in brain. Defects in RAB27A cause Griscelli syndrome type 2 (GS2). Source: Recombinant corresponding to aa1-221 of human RAB27A 6x his tagged, expressed in E.coli. AA Sequences: MGSSHHHHHH SSGLVPRGSH MSDGDYDYLI KFLALGDSGV GKTSVLYQYT DGKFNSKFIT TVGIDFREKR VVYRASGPDG ATGRGQRIHL QLWDTAGQER FRSLTTAFFR DAMGFLLLFD LTNEQSFLNV RNWISQLQMH AYCENPDIVL CGNKSDLEDQ RVVKEEEAIA LAEKYGIPYF ETSAANGTNI SQAIEMLLDL IMKRMERCVD KSWIPEGVVR SNGHASTDQL SEEKEKGACG Molecular Weight: 27kD (241aa), confirmed by MALDI-TOF Enzyme Activity: Not determined. This |
Size | 100ug |
Concentration | n/a |
Applications | n/a |
Other Names | RAB27A, aa1- 221, Recombinant, Human (GTP-binding Protein Ram, MGC117246, RAB27, Rab-27, RAM, Ras-related Protein Rab-27A) |
Gene, Accession, CAS # | Accession: NP_899059 |
Catalog # | R0009-85 |
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Order / More Info | RAB27A, aa1- 221, Recombinant, Human from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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