| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD49e |
|---|
| Clone | HMα5-1 |
|---|
| Host Species | Armenian Hamster |
|---|
| Reactive Species | mouse, rat |
|---|
| Isotype | IgG |
|---|
| Format | purified, azide-free |
|---|
| Size | 500 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC), Block, IP |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | LEAF™ Purified anti-mouse/rat CD49e. CD49e is a 135 kD protein, also known as α5 integrin or VLA-5 α chain. It is a member of the integrin family, expressed on thymocytes, splenic B cells, activated T cells, and mast cells. CD49e associates with CD29 (integrin β1 chain) to form the fibronectin receptor (VLA-5). CD49e plays a critical role in both adhesion and T cell costimulation. The primary ligand for CD49e/CD29 (VLA-5) is fibronectin. The HMα5-1 antibody has been shown to partially block CD49e mediated interactions. It has also been observed that plate-bound HMα5-1 antibody enhances IgE mediated degranulation and that in vivo injection of HMα5-1 antibody, in combination with anti-CD49d and anti-CD61 antibodies, blocks passive cutaneous anaphylaxis. |
|---|
| Immunogen | Affinity-Purified mouse VLA-5 protein (α5β1, CD49e/CD29) |
|---|
| Other Names | α5 integrin, VLA-5 α chain, Integrin α5 |
|---|
| Gene, Accession # | Gene ID: 16402, 315346 |
|---|
| Catalog # | 103908 |
|---|
| Price | |
|---|
| Order / More Info | CD49e Antibody from BIOLEGEND |
|---|
| Product Specific References | PubMed: 20360401 |
|---|
| 产品资料 |
|
|