| 产品详情 |
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| Antigenic Specificity | CD51 |
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| Clone | NKI-M9 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, κ |
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| Format | purified, azide-free |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Immunofluorescence Microscopy (IF), ELISA, Block, IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LEAF™ Purified anti-human CD51. CD51 is a type I integral membrane glycoprotein, known as vitronectin receptor α chain, or integrin αV. It forms heterodimer with integrin β1 (CD29), β3 (CD61), β5, β6, or β8. CD51 contains two disulfide-linked subunits of 125 kD and 24 kD, and is expressed on endothelial cells, fibroblasts, macrophages, platelets, osteoclasts, neuroblastoma, melanoma, and hepatoma cells. Many extracellular matrix proteins with RGD-motifs are CD51 ligands. In association with its β chains, CD51 binds vitronectin, von Willebrand factor, fibronectin, thrombospondin, osteopontin, fibrinogen, and laminin. CD51, as an adhesion molecule, plays important roles in leukocytes homing and rolling, mediates bone absorption and angiogenesis. |
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| Immunogen | Melonama cells |
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| Other Names | αV integrin, Vitronectin receptor α chain, Integrin αV |
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| Gene, Accession # | Gene ID: 3685 |
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| Catalog # | 327904 |
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| Price | |
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| Order / More Info | CD51 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 1693624,1869591,12477667,19038268,23327927 |
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