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| Product Name | Bence Jones kappa Protein, Human |
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| Description | Purity ~90%. Purified by Gel filtration, Ion-exchange and affinity chromatography. A Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22-24kD.[1] Detection of Bence Jones protein may be suggestive of multiple myeloma or Waldenstrom's macroglobulinemia. Bence Jones proteins are particularly diagnostic of multiple myeloma in the context of end-organ manifestations such as renal failure, lytic (or punched out) bone lesions, anemia, or large numbers of plasma cells in the bone marrow of patients. Bence Jones proteins are present in 2/3 of multiple myeloma cases.[2] The proteins are immunoglobulin light chains (paraproteins) and are produced by neoplastic plasma cells. They can be kappa (most of the time) or lambda.[2] The light chains can be immunoglobulin fragments or single homogeneous immunoglobulins. They are found in urine as a result of decreased kidney filtration capabilities due to renal failure, som |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | B1036-50 |
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| Order / More Info | Bence Jones kappa Protein, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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