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Product Name | Serpin E1/PAI-1, Recombinant, Human, |
Description | Purity ~95% (HPLC, SDS-PAGE). Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. They are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Plasminogen activator inhibitor 1, also known as PAI-1, Endothelial plasminogen activator inhibitor, SERPINE1 and PLANH1, is a secreted protein which belongs to the serpin family. SERPINE1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. Defects in SERPINE1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SERPINE1 defect in |
Size | 10ug |
Concentration | n/a |
Applications | n/a |
Other Names | Serpin E1/PAI-1, Recombinant, Human, (Plasminogen activator inhibitor 1) (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1) |
Gene, Accession, CAS # | n/a |
Catalog # | 167960 |
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Order / More Info | Serpin E1/PAI-1, Recombinant, Human, from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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