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Product Name | CD134, Recombinant, Human, aa29-216 |
Description | Purity ~98% (SDS-PAGE). CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen CD27, B cell antigen CD40, FAS antigen and the T cell activation antigen 4-1BB. The human CD134 protein is expressed only on activated CD4+ T blasts, and its ligand has been identified as gp34. Interactions between CD134 and its ligand in vivo are necessary for the differentiation of activated B cells into highly immunoglobulin-producing cells, however not involved in other pathways of antigen-driven differentiation of B cells such as development of memory cells in the germinal centers. In addition, the CD134 and gp34 system directly mediate adhesion of activated T cells to vascular endothelial cells, and contribute to growth stimulation of the virus-infected T cells. Source: Recombinant protein corresponding to aa29-216 from human CD134, fused to the |
Size | 50ug |
Concentration | n/a |
Applications | n/a |
Other Names | CD134, Recombinant, Human, aa29-216 (OX40, Tumor Necrosis Factor Receptor Superfamily Member 4, TNFRSF4, ACT35, TXGP1L) |
Gene, Accession, CAS # | n/a |
Catalog # | 207101 |
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Order / More Info | CD134, Recombinant, Human, aa29-216 from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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