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Product Name | CD14, Recombinant, Human, aa20-345, GST-Tag (Monocyte Differentiation Antigen CD14) |
Description | Purity ~90% (SDS-PAGE). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. Source: Recombinant protein corresponding to aa20-345 from human Monocyte Differentiation Antigen CD14, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~62.2kD AA |
Size | 10ug, 50ug, 100ug |
Concentration | n/a |
Applications | n/a |
Other Names | Myeloid cell-specific leucine-rich glycoprotein, CD14 |
Gene, Accession, CAS # | SwissProt: P08571 |
Catalog # | 372653 |
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Order / More Info | CD14, Recombinant, Human, aa20-345, GST-Tag (Monocyte Differentiation Antigen CD14) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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