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| Product Name | CD33, Recombinant, Human, aa18-259, hIgG-His-tag |
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| Description | Purity ~90% (SDS-PAGE). CD33, also known as myeloid cell surface antigen CD33 isoform 1, is a member of the Ig superfamily that is restricted to cells of the myelomonocytic lineage but whose functions and binding properties are unknown. It can function as a sialic acid-dependent cell adhesion molecule and that binding can be modulated by endogenous sialoglycoconjugates when it is expressed in a plasma membrane. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. It contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that are implicated in inhibition of cellular activity. It has been identified to modulate the risk of Alzheimer's disease (AD) in several recent genome-wide association studies (GWAS) in Caucasians. Recombinant human CD33, fused to hIgG-His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa18-259 of human CD33, fused to hIgG-His-Tag at C-termi |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CD33, Recombinant, Human, aa18-259, hIgG-His-Tag (Myeloid Cell Surface Antigen CD33 Isoform 1, CD33, FLJ00391, p67, SIGLEC-3, SIGLEC3) |
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| Gene, Accession, CAS # | Accession: NP_001763 |
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| Catalog # | 396844 |
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| Order / More Info | CD33, Recombinant, Human, aa18-259, hIgG-His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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