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| Product Name | CD47, Recombinant, Human, aa19-141, hIgG-His-Tag (Leukocyte Surface Antigen CD47 Isoform 1) |
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| Description | Purity ~95% (SDS-PAGE). CD47, also known as leukocyte surface antigen CD47 isoform 1, is a member of immunoglobulin superfamily. It has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Also, it plays an important role in memory formation and synaptic plasticity in the hippocampus. This protein is a receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 mediates cell-cell adhesion, enhances super antigen-dependent T-cell-mediated proliferation and co-stimulates T-cell activation. It may play a role in membrane transport and/or integrin dependent signal transduction and prevent premature elimination of red blood cells. Source: Recombinant protein corresponding to aa19-141 from human CD47, fused to hlgG-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~40.9kD (362aa) 40-57KD (SDS-PAGE under reducing conditions.) AA |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001768 |
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| Catalog # | 369025 |
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| Order / More Info | CD47, Recombinant, Human, aa19-141, hIgG-His-Tag (Leukocyte Surface Antigen CD47 Isoform 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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