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| Product Name | CD28, Recombinant, Human, aa19-152, hIgG-His-Tag (T-Cell-Specific Surface Glycoprotein CD28, Tp44) |
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| Description | Purity ~90% (SDS-PAGE). CD28, also known as T-cell-specific surface glycoprotein CD28 isoform 1, is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in particular). CD28/B7 interaction has been shown to prevent apoptosis of activated T cells via the up-regulation of bcl-XL. It ligation has also been shown to regulate Th1/Th2 differentiation. Source: Recombinant protein corresponding to aa24-188 from human CD28, fused to hIgG-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~42.4kD (376aa), 40-57kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (determined by LAL method) AA |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_006130 |
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| Catalog # | 377736 |
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| Order / More Info | CD28, Recombinant, Human, aa19-152, hIgG-His-Tag (T-Cell-Specific Surface Glycoprotein CD28, Tp44) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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