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| Product Name | BioSim™ anti-Ipilimumab (Yervoy®) (Human) ELISA Kit |
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| Description | Ipilimumab (Yervoy®) is a fully human IgG1κ antibody that binds to CTLA-4 (cytotoxic T lymphocyteassociated antigen 4), a molecule on T-cells that is indicated for unresectable or metastatic melanoma. The absence or presence of CTLA-4 can augment or suppress the immune system's T-cell response in fighting disease. Ipilimumab is designed to block the activity of CTLA-4, thereby sustaining an active immune response in its attack on cancer cells. The proposed mechanism of action is indirect, and may be through T-cell - mediated anti-tumor immune responses. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | This ELISA kit is used for Qualitative determination of antibody against Ipilimumab (Yervoy) in serum and plasma |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | E4398-100 |
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| Order / More Info | BioSim™ anti-Ipilimumab (Yervoy®) (Human) ELISA Kit from BIOVISION, INC. |
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| Product Specific References | n/a |
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