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| Product Name | BioSim™ anti-Rituximab (Mabthera®) (Human) ELISA Kit |
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| Description | Rituximab (Mabthera®) is a genetically engineered chimeric murine/human monoclonal antibody specific to CD20. CD20 is an approximately 35 KDa transmembrane phosphoprotein involved in the activation, proliferation, and differentiation of B-lymphocytes. It is absent in terminally differentiated plasma cells. The Fab domain of rituximab binds to the CD20 antigen on B-lymphocytes and the Fc domain recruits immune effector functions to induce apoptosis in B cells. It is used in treating leukemias and lymphomas, some autoimmune disorders, and organ transplant. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | This ELISA kit is used for quantitative measurement of antibody against Rituximab in human serum and plasma |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | E4385-100 |
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| Order / More Info | BioSim™ anti-Rituximab (Mabthera®) (Human) ELISA Kit from BIOVISION, INC. |
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| Product Specific References | n/a |
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