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| Product Name | Ribosomal Protein S6, phosphorylated (Ser235), Immunizing Peptide |
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| Description | Synthetic peptide corresponding to amino acids 229-242 (AKRRRL [pS]SLRASTS) (linear) of human ribosomal protein S6. To effectively promote growth and cell division in a sustained manner, growth factors and mitogens must upregulate translation. Growth factors and mitogens induce the activation of p70 S6 kinase, which in turn phosphorylate the S6 ribosomal protein. Phosphorylation of S6 correlates with an increase in translation, particularly of mRNAs with an oligopyrimidine tract in their 5' untranslated regions. This group of mRNAs (5'TOP) encodes proteins involved in cell cycle progression and proteins that are part of the translational machinery, such as ribosomal proteins and elongation factors. The main in vivo S6 ribosomal protein phosphorylation sites, including Ser235, Ser236, Ser240 and Ser244, have been identified and are located within a small 19 amino acid region at its carboxyl terminus. Molecular Weight: 1668D Quantity: As reported |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | R2031-35 |
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| Order / More Info | Ribosomal Protein S6, phosphorylated (Ser235), Immunizing Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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