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| Product Name | AGI-6780 |
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| Description | MW: 481.51. Purity ≥98% by HPLC. AGI-6780 is a potent; selective inhibitor of mutant Isocitrate dehydrogenase 2 (IDH2) (IC50= 23 nM). It binds allosterically at the dimer interface of mutant IDH2-R140Q; inhibiting 2-hydroxyglutarate (2-HG) formation in human glioblastoma U87 and TF-1 cells expressing IDH2-R140Q with IC50 values of 11 and 18 nM; respectively. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [N-cyclopropyl-4- (thiophen-3-yl)-3- (3- (3- (trifluoromethyl) phenyl) ureido) benzenesulfonamide] |
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| Gene, Accession, CAS # | CAS: 1432660-47-3 |
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| Catalog # | MBS845803 |
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| Order / More Info | AGI-6780 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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