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| Product Name | Recombinant Rat Kynurenine 3-monooxygenase (Kmo), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 59.5kDa. Partial: 1-384aa. N-terminal 6xHis-SUMO-tagged. Rattus norvegicus (Rat). Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Kynurenine 3-hydroxylase |
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| Gene, Accession, CAS # | Kmo, UniProt: O88867 |
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| Catalog # | RPC21571 |
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| Order / More Info | Recombinant Rat Kynurenine 3-monooxygenase (Kmo), partial from BIOMATIK |
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| Product Specific References | n/a |
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