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| Product Name | Reversan |
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| Description | Selective inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp). Increases the sensitivity of MRP1-overexpressing tumor cells (MCF7/VP) to doxorubicin (Cat. No. 2252), vincristine (Cat. No. 1257) and etoposide (Cat. No. 1226) by 3.8-, 14.6- and 11.6-fold respectively. Increases the efficacy of vincristine and etoposide in murine models of neuroblastoma in vivo. Does not sensitize MRP2, MRP3, MRP4 or MRP5 transporters to known substrates. Purity 99%. MW (observed): 441.52 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[3-(4-Morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide |
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| Gene, Accession, CAS # | CAS: 313397-13-6 |
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| Catalog # | 3722/10 |
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| Order / More Info | Reversan from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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