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| Product Name | CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric |
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| Description | Background: Neoplastic transformation occurs via a series of genetic and epigenetic alterations that yield a cell population that is capable of proliferating independently of both external and internal signals that normally restrain growth. For example, transformed cells show reduced requirements for extracellular growth promoting factors, are not restricted by cell-cell contact, and are often immortal. Anchorage-independent growth is one of the hallmarks of transformation, which is considered t |
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| Size | 24 assays, 96 assays, 480 assays, |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS168666 |
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| Order / More Info | CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric from MYBIOSOURCE INC. |
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| Product Specific References | 1. Shin SI, Freedman VH, Risser R, and Pollack R. (1975) Proc Natl Acad Sci U S A. 72:4435-9.2. Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW and Weinberg RA. (1999) Nature 400:464-8.1. Hong, S.W. et al. (2012). Ring Finger Protein 149 Is an E3 Ubiquitin Ligase Active on Wild-type v-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF). J. Biol. Chem. 287:24107-24025.2. Lee, H.J. et al. (2012). Chemokine (C-X-C Motif) Ligand 12 Is Associated with Gallbladder Carcinoma Progression and Is a Novel Independent Poor Prognostic Factor. Clin. Cancer. Res. 18:3270-3280.3. Chapeau, E.A. et al.(2012).Ecotopic Viral Integration Site 1 (EVI1) Regulates Multiple Cellular Processes Important for Cancer and is a Synergistic Partner for FOS Protein in Invasive Tumors. Proc Natl Acad Sci 109:2168-2173.4. Lim, S.K. et al. (2011). Tyrosine Phosphorylation of Transcriptional Coactivator WW-Domain Binding Protein 2 Regulates Estrogen Receptor a Function in Breast Cancer via the Wnt Pathway. FASEB J. 25:3004-3018.5. Mathew, B. et al. (2011). The Novel Role of the Mu Opioid Receptor in Lung Cancer Progression: A Laboratory Investigation. Anesth. Analg. 112:558-567.6. Hirata, H. et al. (2010). Role of secreted Frizzled-Related Protein3 in Human Renal Cell Carcinoma. Cancer Res. 70:1896-1905.7. Xie, G. et al. (2009). Acetylcholine-Induced Activation of M3 Muscarinic Receptors Stimulates Robust Matrix Metalloproteinase Gene Expression in Human Colon Cancer Cells. Am. J. Physiol. Gastrointest. Liver Physiol. 296:G755-G763.8. Ke, X-S. et al. (2008). Epithelial to Mesenchymal Transition of a Primary Prostate Cell Line with Switches of Cell Adhesion Modules but Without Malignant Transformation. PLoS One 3(10):e3368. |
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