| 产品详情 |
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| Product Name | R 568 hydrochloride |
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| Description | Positive allosteric modulator and allosteric agonist of the human calcium-sensing receptor (hCaSR). Exhibits calcimimetic activity. Has the ability to restore function to hCaSR mutants that cause familial hypocalciuric hypercalcemia (FHH) and neonatal severe hyperparathyroidism (NSHPT). Exerts a suppressive effect on parathyroid (PT) hormone secretion; inhibits PT cell proliferation in rats with renal insufficiency. Purity 99%. MW (observed): 340.29 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine hydrochloride |
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| Gene, Accession, CAS # | CAS: 177172-49-5 |
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| Catalog # | 3815/10 |
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| Order / More Info | R 568 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22517767, 22730443, 23143333, 24327954, 25904744, 26375676, 26893368 |
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