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| Product Name | SFRP3, Recombinant, Human (Secreted Frizzled Related Protein 3, FRZB, Fritz, Frzb1) |
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| Description | Purity ≥95%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin: ≤1EU/ug (LAL). Secreted Frizzled Related Protein 3 (SFRP3) was originally identified in bovine cartilage for its chondrogenic ability. Human, mouse, chick and Xenopus clones have also been isolated. SFRP3 is often referred to as FRZB, other names include Fritz, Frzb1, and FRP-3. At the amino acid sequence level, SFRP3 is highly conserved. The human protein shares 77% identity with Xenopus, 92% with mouse and 94% with bovine proteins. Human SFRP3 is strongly expressed in the developing appendicular skeleton and cartilage of craniofacial bones. As determined by Northern blot of adult tissues, it is strongly detected in heart and placenta, as well as the brain, skeletal muscle kidney and pancreas. The N-terminal portion of the protein shows 50% amino acid identity to the corresponding region of the Drosophila frizzled gene product, a receptor for Wg/Wnt signals. The similarity of SF |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 2487, Accession: AAB51298 |
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| Catalog # | S1012-88R |
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| Order / More Info | SFRP3, Recombinant, Human (Secreted Frizzled Related Protein 3, FRZB, Fritz, Frzb1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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