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| Product Name | Beta-NGF, Recombinant, Human, Animal Free (beta-Nerve Growth Factor) |
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| Description | Purity ~98% (SDS-PAGE gel, HPLC). beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4.These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. beta-NGF is a potent neurotrophic factor that signals through its receptor beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival.The functional form of human beta-NGF is a noncovalently disulfide-linked homodimer, of two 13.5kD polypeptide monomers (240 total amino acid residues). The three disulfide bonds are required for biological activity. Source: Recombinant protein corresponding to human Beta-NGF expressed in E. coli. Biological Activity: Assay #1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED50 is ≤1.0ng/ml, corresponding to a specific activ |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | beta-Nerve Growth Factor |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208603 |
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| Order / More Info | Beta-NGF, Recombinant, Human, Animal Free (beta-Nerve Growth Factor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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