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| Product Name | β-NGF, Recombinant, Mouse |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4.These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures.beta-NGF is a potent neurotrophic factor that signals through its receptor beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival.The functional form of murine beta-NGF is a noncovalently disulfide-linked homodimer, of two 13.4kD polypeptide monomers (240 total amino acid residues).The three disulfide bonds are required for biological activity. Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ~1.0ng/ml, corresponding to a specific activity of ~1x10e6 units/mg. AA Sequence: SSTHPVFHMG EFSVCDSVSV WVGDKTTATD IKGKEVTVLA EVNIN |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143511 |
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| Order / More Info | β-NGF, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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