| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human HB-EGF Protein |
|---|
| Description | HB-EGF is an EGF related growth factor that signals through the EGF receptor, and stimulates the proliferation of smooth muscle cells (SMC), fibroblasts, epithelial cells, and keratinocytes. HB-EGF is expressed in numerous cell types and tissues, including vascular endothelial cells and SMC, macrophages, skeletal muscle, keratinocytes, and certain tumor cells. The ability of HB-EGF to specifically bind heparin and heparin sulfate proteoglycans is distinct from other EGF-like molecules, and may be related to the enhanced mitogenic activity, relative to EGF, that HB-EGF exerts on smooth muscle cells. The human HB-EGF gene encodes a 208 amino acid transmembrane protein, which can be proteolytically cleaved to produce soluble HB-EGF. Recombinant human HB-EGF is a 9.7 kDa protein containing 86 amino acid residues, corresponding to the extra-cellular EGF-like and heparin binding domains of the full length HB-EGF protein. |
|---|
| Size | Various Sizes |
|---|
| Concentration | n/a |
|---|
| Applications | Cell Culture |
|---|
| Other Names | Proheparin-binding EGF-like growth factor;Heparin-binding EGF-like growth factor;HB-EGF;HBEGF;Diphtheria toxin receptor;DT-R;HBEGF;DTR, DTS, HEGFL; Heparin Binding EGF-like growth factor, HBEGF, Diphtheria toxin receptor, DTR |
|---|
| Gene, Accession, CAS # | HBEGF, UniProt: Q99075 |
|---|
| Catalog # | PROTQ99075-2 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human HB-EGF Protein from BOSTER BIO |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|