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Product Name | SL 327 |
Description | Selective inhibitor of MEK1 and MEK2 (IC50 values are 0.18 and 0.22 μM respectively); blocks hippocampal LTP in vitro. Brain penetrant in vivo, blocking fear conditioning and learning in rats, and producing neuroprotection in mice, following systemic administration. Purity 99%. MW (observed): 335.35 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | α-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile |
Gene, Accession, CAS # | CAS: 305350-87-2 |
Catalog # | 1969/50 |
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Order / More Info | SL 327 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 16051150, 16482086, 16954211, 19125235, 19371583, 20739576, 20980993, 21084617, 21430174, 22108021, 23693126, 25181481, 25261469, 25383899, 25385607, 25918399, 27211495 |
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