| 产品详情 |
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| Antigenic Specificity | CD45RB |
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| Clone | C363-16A |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | Alexa Fluor® 647 conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alexa Fluor® 647 anti-mouse CD45RB. CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, naïve T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naïve to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1. |
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| Immunogen | Cloned mouse Th2 cell lines |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 19264 |
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| Catalog # | 103311 |
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| Price | |
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| Order / More Info | CD45RB Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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