产品名称 |
CSF1, Recombinant, Human, aa33-255, His-Tag (Macrophage Colony-Stimulating Factor 1, M-CSF, MCSF, Lanimostim) from UNITED STATES BIOLOGICAL |
产品详情 |
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Product Name | CSF1, Recombinant, Human, aa33-255, His-Tag (Macrophage Colony-Stimulating Factor 1, M-CSF, MCSF, Lanimostim) |
Description | Purity ~95% (SDS-PAGE). CSF1, also known as macrophage colony-stimulating factor 1, is a hematopoietic growth factor that is the primary regulator of the survival, proliferation, differentiation and function of mononuclear phagocytes. It is a four alpha-helical bundle cytokine and its active form is found extracellularly as a disulfide linked homodimer. This protein plays important roles in innate immunity, cancer and inflammatory diseases, including systemic lupus erythematosus, arthritis, atherosclerosis and obesity. In several conditions, activation of macrophages involves a CSF1 autocrine loop. In addition, secreted and cell-surface isoforms of CSF1 can have differential effects in inflammation and immunity. Source: Recombinant protein corresponding to aa33-255 from human CSF1, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~26.1kD (231aa), 28-40kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) Biological Activity: Measured in a cell proli |
Size | 10ug, 50ug |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | Accession: NP_000748, SwissProt: P09603 |
Catalog # | 377773 |
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Order / More Info | CSF1, Recombinant, Human, aa33-255, His-Tag (Macrophage Colony-Stimulating Factor 1, M-CSF, MCSF, Lanimostim) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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