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Product Name | Csf1, Recombinant, Rat (Macrophage Colony-stimulating Factor 1, CSF-1, MCSF, Csfm) |
Description | Purity ~98% (SDS-PAGE and HPLC). M-CSF is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. The human is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant rat M-CSF is a 18.1kD homodimeric protein containing two 155aa polypeptide subunits. Source: Recombinant protein corresponding to rat M-CSF, expressed in E.coli. Biological Activity: Determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells |
Size | 2ug, 10ug |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | 149722 |
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Order / More Info | Csf1, Recombinant, Rat (Macrophage Colony-stimulating Factor 1, CSF-1, MCSF, Csfm) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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