产品详情 |
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Antigenic Specificity | MPL |
Clone | 1.6.1 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | FC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse Anti-MPL Recombinant Antibody (1.6.1). This product is antibody recognizes MPL. The antibody 1.6.1 immunoassay techniques such as: FC. In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c-mpl, was cloned. Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation. The ligand for c-mpl, thrombopoietin, was cloned in 1994. Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet |
Immunogen | n/a |
Other Names | MPL Proto-Oncogene, Thrombopoietin Receptor; Myeloproliferative Leukemia Virus Oncogene; Myeloproliferative Leukemia Protein; Proto-Oncogene C-Mpl; TPO-R; TPOR; Thrombopoietin Receptor; |
Gene, Accession # | Gene ID: 4352, UniProt: P40238 |
Catalog # | CBMAB-C9437-LY |
Price | |
Order / More Info | MPL Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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