产品详情 |
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Antigenic Specificity | Tnfrsf10b |
Clone | CBYJT-3660 |
Host Species | Recombinant Rat |
Reactive Species | mouse |
Isotype | IgG2 |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat Anti-Tnfrsf10b Recombinant Antibody (CBYJT-3660). Provided herein is a Rat monoclonal antibody, which binds to Tnfrsf10b (Tumor Necrosis Factor Receptor Superfamily, Member 10B). The antibody can be used for immunoassay techniques, such as IHC, WB. Tnfrsf10b is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. It promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. |
Immunogen | Recombinant protein corresponding to mouse TNFRSF10B |
Other Names | MK; DR5; Ly98; KILLER; TRICKB; TRAILR2; TRICK2A; TRICK2B |
Gene, Accession # | Gene ID: 21933, UniProt: Q9QZM4 |
Catalog # | CBMAB-T3029-YJ |
Price | |
Order / More Info | Tnfrsf10b Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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