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Product Name | bpV(HOpic) (potassium salt, technical grade) |
Description | Purity >80%. bpV(HOpic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 14 nM). It also inhibits the vascular endothelial PTP, PTP-Beta (IC50 = 4.9 µM), and PTP-1BetaB (IC50 = 25.3 µM). At 15 µM, bpV(HOpic) has been shown to protect against stimulated ischemia-reperfusion injury in vitro by decreasing apoptosis and improving cell viability through the upregulation of the PI3K/Akt/eNOS/ERK prosurvival pathway. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | (5-hydroxy-2-pyridinecarboxylato-?N1 ,?O2 )oxodiperoxy-vanadate(2-), dipotassium, Bisperoxovanadium(HOpic) |
Gene, Accession, CAS # | CAS: 722494-26-0 |
Catalog # | LS-H6882 |
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Order / More Info | bpV(HOpic) (potassium salt, technical grade) from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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