| 产品详情 |
| Edit |   |
|---|
| Product Name | VE 821 |
|---|
| Description | High affinity and selective ATP-competitive ATR inhibitor (Ki = 13 nM). Exhibits >75-fold selectivity for ATR over related kinases mTOR, DNA-PK, PI 3-Kγ and PIKKs (Ki values are >1, 2.2, 3.9 and 16 μM, respectively) and a panel of other kinases. Induces cell death in colon cancer cell lines in vitro and sensitizes tumor cells to treatment with DNA damaging anticancer agents. Purity 98%. MW (observed): 368.41 |
|---|
| Size | 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 3-Amino-6-[4-(methlsulfonyl)phenyl)-N-phenyl-2-pyrazinecarboxamide |
|---|
| Gene, Accession, CAS # | CAS: 1232410-49-9 |
|---|
| Catalog # | 6160/5 |
|---|
| Price | |
|---|
| Order / More Info | VE 821 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|