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| Product Name | GDF-15-D, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Growth and differentiation factor 15 (GDF-15) is a TGFbeta family member, made by in the placenta and heart tissues, that has a role in regulating inflammatory and apoptotic pathways. GDF-15 has become an immerging marker of early heart disease and has the potential as being used as a molecule for screening patients for early heart failure. Recombinant human GDF-15 (D-variant) is a non-glycosylated, disulfide linked homodimer. There is a His to an Asp substitution at position 7. Source: Recombinant protein corresponding to two identical 120aa chains from human GDF-15-D, expressed in E. coli. Molecular Weight: ~26.8kD Biological Activity: Determined by the inhibition of DU-145 cells and is typically 1-2ug/ml. Endotoxin: <0.01ng/ug AA Sequence: MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLI QKTDTGVSLQ TYDDLLAKDC HCI |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GDF-15-D, Recombinant, Human (GDF-15 (D-variant), MIC-1, Placental TGFbeta, Prostate Differentiation Factor) |
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| Gene, Accession, CAS # | GDF-15, Gene ID: 9518, SwissProt: Q99988 |
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| Catalog # | 219788 |
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| Order / More Info | GDF-15-D, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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