| 产品详情 |
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| Product Name | Interleukin 7 (IL7) (C-Term) protein |
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| Description | Recombinant Human Interleukin-7/IL-7 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Asp26-His177) of Human IL-7 fused with a polyhistidine tag at the C-terminus. Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 AA precursor protein containing a 25 AA signal peptide and a 152 AA mature protein. Human and mouse IL7 share 65 % sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R γ for signal transduction. |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL7|IL-7|A630026I06Rik|Il-7|hlb368 |
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| Gene, Accession, CAS # | Gene ID: 3574 |
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| Catalog # | ABIN1691666 |
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| Order / More Info | Interleukin 7 (IL7) (C-Term) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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