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| Product Name | CTDSP1, 1-260aa, Human, His tag, E Coli |
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| Description | MW: 31.2 kDa (280aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. Carboxy-terminal domain, RNA polymerase II, polypeptide A phosphatase 1, also known as CTDSP1, is a class 2C phosphatase with activity dependent on the conserved DxD motif. CTDSP1 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Also it negatively regulates RNA polymerase II transcription, possibly by |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Carboxy-terminal domain RNA polymerase II polypeptide A phosphatase 1; Carboxy-terminal domain; RNA polymerase II; polypeptide A phosphatase 1; NLIIF; SCP1; NIF3] |
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| Gene, Accession, CAS # | CTDSP1, Gene ID: 58190, Accession: NP_872580 |
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| Catalog # | MBS203810 |
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| Order / More Info | CTDSP1, 1-260aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Maiello B., et al. (2001) Front Biosci. 6: 1358-1368.; Palancade B., et al. (2004) J Mol Biol. 335:415-424. |
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