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| Product Name | Aminopeptidase N (APN/CD13) Activity Assay Kit (Fluorometric) |
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| Description | Aminopeptidase N (APN, EC 3.4.11.2) also known as CD13 or membrane alanyl aminopeptidase is a Zn2+-dependent ectopeptidase that cleaves N-terminal neutral amino acids (preferentially alanine) from proteins and peptides. APN is a promiscuous, multifunction enzyme consisting of a short cytoplasmic domain, a single transmembrane helix and a large extracellular catalytic domain that can be cleaved to generate a soluble version of the enzyme. Aminopeptidase N expression is upregulated in many different human cancers and the enzyme is involved in metastatic tumor cell proliferation, invasion and angiogenesis. Serum levels of soluble APN are elevated in cancer patients compared with healthy controls and there is a strong inverse correlation betwee |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | Detection of CD13 activity in mammalian tissues, cell culture and purified enzyme |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K523-100 |
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| Order / More Info | Aminopeptidase N (APN/CD13) Activity Assay Kit (Fluorometric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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