产品详情 |
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Product Name | Recombinant Human MMP-3 Protein |
Description | Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-3 degrades fibronectin, laminin, collagens III, IV, and X, and cartilage proteoglycans. Recombinant human MMP-3 is a 42.8 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (378 amino acids). |
Size | Various Sizes |
Concentration | n/a |
Applications | Cell Culture |
Other Names | Stromelysin-1;SL-1;3.4.24.17;Matrix metalloproteinase-3;MMP-3;Transin-1;MMP3;STMY1; Stromelysin-1, SL-1, Transin-1 |
Gene, Accession, CAS # | MMP3, UniProt: P08254 |
Catalog # | PROTP08254-3 |
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Order / More Info | Recombinant Human MMP-3 Protein from BOSTER BIO |
Product Specific References | n/a |
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