| 产品详情 |
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| Antigenic Specificity | LSD1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LSD1 Polyclonal Antibody. LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3. This protein may play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the presence |
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| Immunogen | n/a |
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| Other Names | Lysine-specific histone demethylase 1; Amine oxidase flavin containing domain protein 2; BRAF35-HDAC complex protein BHC110; AOF2; KIAA0601; KDM1 |
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| Gene, Accession # | Entrez: 23028; Uniprot: O60341 |
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| Catalog # | PA5-11308 |
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| Price | |
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| Order / More Info | LSD1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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