| 产品详情 |
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| Antigenic Specificity | LSD1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LSD1 Polyclonal Antibody. LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3. This protein may play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the presence |
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| Immunogen | n/a |
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| Other Names | RP1-184J9.1, AOF2, BHC110, KDM1, LSD1; BRAF35-HDAC complex protein BHC110; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; amine oxidase (flavin containing) domain 2; flavin-containing amine oxidase domain-containing protein 2; lysine (K)-specific demethylase 1; lysine-specific histone demethylase 1; lysine-specific histone demethylase 1A |
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| Gene, Accession # | Entrez: 23028, 500569, 99982; Uniprot: O60341, Q6ZQ88 |
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| Catalog # | PA5-20227 |
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| Price | |
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| Order / More Info | LSD1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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