| 产品详情 |
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| Antigenic Specificity | PCBP4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1 µg/mL, Immunofluorescence: 20 µg/mL, Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PCBP4 Polyclonal Antibody. MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have b |
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| Immunogen | n/a |
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| Other Names | CBP, LIP4, MCG10; LYST-interacting protein; RNA binding protein MCG10; alpha-CP4; poly(rC)-binding protein 4 |
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| Gene, Accession # | Entrez: 57060; Uniprot: P57723 |
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| Catalog # | PA5-20359 |
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| Price | |
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| Order / More Info | PCBP4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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