| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | OXSR1 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1:500-1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | OXSR1 Polyclonal Antibody. Oxidative stress-responsive 1 protein (OXSR1), a protein of 527 amino acids, belongs to the STE20 subfamily. OXSR1 is one of two human homologs of Fray, a serine/threonine kinase expressed in Drosophila. OXSR1 binds to and phosphorylates p21-activated protein kinase PAK1 and regulates downstream kinases in response to environmental stress. Endogenous OXSR1 is activated only by osmotic stresses, notably sorbitol and to a lesser extent NaCl. OXSR1 may also play a role in regulating the actin cytoskeleton. The chloride channel proteins SLC12A1, SLC12A2, and SLC12A6 isoform 2 interact with OXSR1, but SLC12A4 and SLC12A7 do not. The WNK1 and WNK4 protein kinases activate OXSR1 by phosphorlating its T-loop. The OXSR1 pr |
|---|
| Immunogen | n/a |
|---|
| Other Names | Serine/threonine-protein kinase OSR1; Oxidative stress-responsive 1 protein; KIAA1101; OSR1 |
|---|
| Gene, Accession # | Entrez: 108737, 316064, 9943; Uniprot: O95747, Q6P9R2 |
|---|
| Catalog # | PA5-75543 |
|---|
| Price | |
|---|
| Order / More Info | OXSR1 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|