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Product Name | Purvalanol B |
Description | Cyclin-dependent kinase (cdk) inhibitor (reported IC50 values are 6 nM for cdk1 and cdk5, and 6 - 9 nM for cdk2, depending on binding partner). Selective over a range of other protein kinases (IC50 >10,000 nM). Shown to have antiproliferative properties, mediated by ERK1 and ERK2. Purity 99%. MW (observed): 432.91 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (2R)-2-[[6-[(3-Chloro-4-carboxyphenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol. NG 95 |
Gene, Accession, CAS # | CAS: 212844-54-7 |
Catalog # | 1581/10 |
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Order / More Info | Purvalanol B from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 17192257, 20071362 |
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