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| Antigenic Specificity | p300 |
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| Clone | 7D8A6 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1/500 - 1/2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p300 Monoclonal Antibody (7D8A6). This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A , and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. |
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| Immunogen | n/a |
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| Other Names | p300; KAT3B; EP300 |
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| Gene, Accession # | Entrez: 2033; Uniprot: Q09472 |
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| Catalog # | MA5-15444 |
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| Price | |
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| Order / More Info | p300 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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