| 产品详情 |
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| Antigenic Specificity | p300 |
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| Clone | NM-11 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Immunofluorescence: Assay Dependent, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p300 Monoclonal Antibody (NM-11). EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. |
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| Immunogen | n/a |
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| Other Names | p300, KAT3B, EP300 |
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| Gene, Accession # | Entrez: 2033; Uniprot: Q09472 |
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| Catalog # | 33-7600 |
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| Price | |
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| Order / More Info | p300 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12917425, 17344210, 20385574, 25068129 |
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