| 产品详情 |
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| Antigenic Specificity | p300 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ChIP assay: 1-3 µL, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p300 Polyclonal Antibody. Cyclic AMP-responsive enhancer binding protein (CREB) binding protein (CBP) and p300 are closely related transcriptional coactivators and have been shown to directly interact with many different DNA-binding transcription factors including nuclear hormone receptors, CREB, c-Fos, c-Jun/v-Jun, c-Myb/v-Myb, TFIIB and MyoD. Both CBP and p300 have been shown to display histone acetyltransferase (HAT) activity, capable of acetylating all four core histone particles in nucleosomes. As a result of HAT activity, it has been suggested CBP and p300 may play a direct role in activating chromatin for transcription. Single point mutations in CBP have been proposed as causative factors in the developmental abnormalities of Rubinst |
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| Immunogen | n/a |
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| Other Names | EP300 |
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| Gene, Accession # | Entrez: 2033; Uniprot: Q09472 |
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| Catalog # | PA1-848 |
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| Price | |
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| Order / More Info | p300 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26105050 |
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