| 产品详情 |
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| Antigenic Specificity | Ku80 |
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| Clone | S.669.4 |
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| Host Species | Rabbit |
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| Reactive Species | human, nonhuman primate |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:400, Immunofluorescence: 1:400, Immunohistochemistry (Frozen): 1:800, Immunohistochemistry (Paraffin): 1:800, Immunoprecipitation: 1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Ku80 Monoclonal Antibody (S.669.4). The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
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| Immunogen | n/a |
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| Other Names | 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku autoantigen, 80kDa; Ku86 autoantigen related protein 1; OTTHUMP00000164061; OTTHUMP00000206791; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kD); X-ray repair cross-complementing protein 5; X-ray repair, complementing de |
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| Gene, Accession # | Entrez: 7520; Uniprot: P13010 |
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| Catalog # | MA5-14953 |
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| Price | |
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| Order / More Info | Ku80 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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